Debra Messing and Dermot Mulroney present the nominees for the 31st Annual "Favorite On-Screen Chemistry" People's Choice Award.
Debra Messing and Dermot Mulroney of The Wedding Date present Drew Barrymore and Adam Sandler in 50 First Dates; Kate Winslet and Johnny Depp in Finding Neverland and Kirsten Dunst and Tobey Maguire in Spiderman 2 as the nominees for the 31st Annual "Favorite On-Screen Chemistry" People's Choice Award.